Substrate specificity of tonin from rat submaxillary gland.

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Substrate specificity of tonin from rat submaxillary gland.

The substrate specificity of tonin from rat submaxillary gland was examined with a series of synthetic peptides encompassing the C-terminus of the decapeptide substrate angiotensin I. In contrast to angiotensin I-converting enzyme from plasma or lung, only angiotensin I, (des-Asp1)-angiotensin I, and (des-Asp1, des-Arg2)-angiotensin I are substrates of tonin with Km values of 34.5 muM, 39.3 muM...

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ژورنال

عنوان ژورنال: Circulation Research

سال: 1976

ISSN: 0009-7330,1524-4571

DOI: 10.1161/01.res.39.5.629